Relatório Final de Estágio Mestrado Integrado em Medicina Veterinária A SEROPREVALENCE STUDY OF ANTIBODIES AGAINST A NOVEL CANINE NOROVIRUS IN CANINE AND HUMAN POPULATIONS
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چکیده
........................................................................................................................................ v Agradecimentos ........................................................................................................................... vi Abbreviations ............................................................................................................................... vii Index ............................................................................................................................................ ix Introduction ................................................................................................................................... 1 Norovirus ................................................................................................................................... 1 Discovery of the Norwalk virus .................................................................................................. 2 Classification of noroviruses ..................................................................................................... 3 Viral structure ............................................................................................................................ 4 Genome organization ................................................................................................................ 6 Transmission and biological characteristics .............................................................................. 7 Virus–cell interactions ............................................................................................................... 7 Pathogenesis ............................................................................................................................ 8 Human noroviruses ............................................................................................................... 8 Bovine noroviruses ................................................................................................................ 8 Porcine noroviruses ............................................................................................................... 9 Lion norovirus ........................................................................................................................ 9 Canine noroviruses ................................................................................................................ 9 Murine noroviruses .............................................................................................................. 10 Immunity .................................................................................................................................. 11 Interspecies transmission of noroviruses and the risk of zoonosis ......................................... 11 Objectives ............................................................................................................................... 12 Materials and Methods ............................................................................................................... 13
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